Evidence map›Paper›PMID 41555455›Full record

ArticleJournal of cardiothoracic surgery2026

Unusual presentation of fungal infective endocarditis as the first manifestation of HIV in a child with a structurally normal heart.

Amber Kamran, Yusra Tariq, Waris Ahmed, Rumana Sangi, Saleem Akhtar

Abstract readCase Reports
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amber KamranDow University of Medical and Health Sciences, Karachi, Pakistan.
Yusra TariqAga Khan University Hospital, Karachi, Pakistan.
Waris AhmedAga Khan University Hospital, Karachi, Pakistan.
Rumana SangiFCPS Paediatric Cardiology Senior Instructor Paediatric Cardiology, Aga Khan University Hospital , Karachi, Pakistan. dr.rumanasangi@yahoo.com.ORCID http://orcid.org/0000-0002-0160-7133
Saleem AkhtarAga Khan University Hospital, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 9-year-old boy who presented with mitral valve perforation secondary to Ustilago species fungal infective endocarditis. Subsequent evaluation revealed previously undiagnosed HIV infection. Fungal endocarditis due to Ustilago species is exceedingly rare, and presentation as the initial manifestation of HIV has not been previously described in the pediatric population. The atypical presentation posed significant diagnostic challenges, emphasizing the need to consider underlying immunodeficiency, including HIV infection, in children presenting with unusual or opportunistic infections. To our knowledge, this represents the first reported case of Ustilago infective endocarditis unveiling pediatric HIV infection in a child with a structurally normal heart.

Indexed as

EndocarditisHIV InfectionsMycosesChildHumansMale

Identifiers

PMID41555455
PMCPMC12895718

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.