ArticleJournal of anesthesia, analgesia and critical care2026
Platelet count, fibrinogen and ROTEM® parameters predict deep vein thrombosis in elderly patients with femoral fracture.
Article in Journal of anesthesia, analgesia and critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Assessment of Hypercoagulability After Orthopedic Trauma Surgery Using Coagulation Biomarkers and TEG/ROTEM.International journal of molecular sciences · 2026Review
- Perioperative Coagulation Dynamics Assessed by ROTEM and Conventional Assays: A Prospective Longitudinal Study with Focus on Fibrinogen in Major Non-Cardiac Surgery.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeep vein thrombosis (DVT) is a frequent complication in elderly patients undergoing surgery for proximal femoral fractures. Identifying early coagulation and viscoelastic changes may help to personalize thromboprophylaxis strategies. This study evaluated the temporal evolution of coagulation and ROTEM parameters and explored whether baseline values and early changes could predict the development of asymptomatic DVT.
methodsWe conducted a prospective observational study including patients ≥ 80 years undergoing surgical repair of proximal femoral fractures. Conventional coagulation tests and ROTEM were performed at admission (T0) and on postoperative day 3 (T3). Compression ultrasonography was used to screen for DVT on day 5 (T5). Longitudinal changes were assessed with linear mixed-effects models.
resultsAmong 40 enrolled patients, 7 (17.5%) developed asymptomatic DVT. Platelet count was consistently higher in DVT patients (baseline: 275.0 ± 47.1 vs 186.5 ± 54.9 × 10
conclusionIn elderly patients with femoral fractures, asymptomatic DVT was associated with elevated baseline platelet counts, enhanced clot firmness, and progressive fibrinogen elevation over time. These findings suggest multifaceted hypercoagulable abnormalities with temporal monitoring potentially superior to single-timepoint assessments for DVT prediction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.