Evidence map›Paper›PMID 41555370›Full record

ArticleJournal of nanobiotechnology2026

Zn

Jingya Xiu, Lin Liu, Lingao Yin, Yihong Peng, Ziqi Li, Ziyun Lin, Yilin Song, Degong Yang, Jiulong Zhang, Chunrong Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jingya XiuDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Lin LiuDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Lingao YinDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Yihong PengDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Ziqi LiDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Ziyun LinDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Yilin SongDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.
Degong YangDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangdg@stu.edu.cn.
Jiulong ZhangCollege of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110000, PR China. zjl1160@163.com.
Chunrong YangDepartment of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangchunrong@stu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunogenic cell death (ICD), instigated by reactive oxygen species (ROS), has emerged as an efficacious strategy for augmenting the immunogenicity of tumor cells. However, the effects of ICD are severely diminished by elevated levels of glutathione (GSH) within tumor cells to maintaining intracellular redox homeostasis. To address this, the novel carrier-free self-assembled nanoparticles are designed to aggravating redox dyshomeostasis by reducing GSH and increasing ROS levels. The nanoparticles (ZDS NPs) were established by the self-assembly of zinc ions (Zn

Indexed as

DoxorubicinImmunogenic Cell DeathNanoparticlesNeoplasmsRNA, Small InterferingZincAnimalsCell Line, TumorGlutathioneHomeostasisHumansMiceNF-E2-Related Factor 2Oxidation-ReductionReactive Oxygen SpeciesDoxorubicinGlutathioneNF-E2-Related Factor 2Reactive Oxygen SpeciesRNA, Small InterferingZincGlutathioneICDReactive oxygen speciesRedox dyshomeostasisSelf-assembled nanoparticles

Identifiers

PMID41555370
PMCPMC12853939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.