Trial reportBMC oral health2026
Non-surgical treatment of peri-implantitis with submarginal erythritol air-polishing in severe periodontitis patients: a randomized controlled trial.
Trial report in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
aimTo evaluate the clinical and radiographic outcomes of non-surgical treatment by either submarginal erythritol air-polishing or combined instrumentation for peri-implantitis in severe periodontitis patients. MATERIALS AND
methodsThis randomized clinical trial enrolled patients diagnosed with stage III/IV periodontitis and peri-implantitis affecting at least one dental implant. The test group received erythritol air-polishing while the control group received ultrasonic combined with manual instrumentation for peri-implant submarginal debridement. The primary outcome was the mean peri-implant probing depth (PPD) at 3 months. Clinical parameters were assessed at baseline (T0), T1 (6 weeks), and T2 (3 months); radiographic parameters were assessed at T0 and T2. Intergroup differences were analyzed using the Mann-Whitney U or t-test at each timepoint and verified by mixed-effects models. Factors potentially influencing PPD prognosis were assessed using Generalized Estimating Equations (GEE).
resultsInitially, 40 patients (20 per group) with peri-implantitis were randomly assigned to the trial; 38 patients completed the study. At T2, mean PPD reduced from 6.0 ± 1.8 mm to 4.2 ± 1.6 mm (test group) and 4.7 ± 1.5 mm (control group) with no significant differences between groups. Mean modified sulcus bleeding index(mSBI) decreased in both groups, with a significantly greater reduction in the test group. The treatment efficacy of PPD can be influenced by keratinized mucosa width (KMW), PPD-T0, mSBI-T2, and probing depth reduction of adjacent teeth.
conclusionsIn patients with severe periodontitis, both non-surgical therapies were effective in improving clinical parameters of peri-implantitis. Erythritol air-polishing exhibited greater improvement in soft tissue inflammation. Adequate peri-implant keratinized mucosa and greater reduction in probing depth of adjacent teeth were identified as favorable prognostic factors for PPD. CLINICAL
trial registrationThis study had retrospectively registered at Chinese Clinical Trial Registry (ChiCTR2100048446) on July 7, 2021 ( https://www.chictr.org.cn/showproj.html? proj=129220 ).
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