Evidence map›Paper›PMID 41555293›Full record

ArticleBMC psychiatry2026

Prevalence and correlates of social dysfunction in community-dwelling patients with bipolar disorder: a cross-sectional study.

LuLu Zhang, Deyuan Wu, Mingshan Ye, Liting Wang, Xiaohua Sun, Mingjin Luo, Haidong Song

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Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

LuLu Zhang *School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, Anhui, 230032, China.
Deyuan Wu *Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310013, China.
Mingshan YeSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, Anhui, 230032, China.
Liting WangSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, Anhui, 230032, China.
Xiaohua SunAffiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310013, China.
Mingjin LuoAffiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310013, China. Luomingjin314@163.com.
Haidong SongSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, Anhui, 230032, China. drsonghaidong@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial dysfunction is common among patients with bipolar disorder (BD) even during remission, underscoring the need to shift toward function-oriented treatment models. This study aimed to quantify the prevalence of social dysfunction in community-dwelling patients with BD and identify multidimensional biopsychosocial influencing factors.

methodsA cross-sectional survey was conducted among 7,952 community-dwelling BD patients in Hangzhou. Social functioning was assessed using the Social Disability Screening Schedule (SDSS), with a score [Formula: see text] indicating dysfunction. Multivariable logistic regression was performed to examine demographic, clinical, and psychosocial correlates.

resultsThe prevalence of social dysfunction among community-dwelling patients with BD was 66.4%. Multivariable analysis identified several independent factors associated with this dysfunction, including divorced status (Adjusted Odds Ratio [AOR] = 1.76, 95% Confidence Interval [CI]: 1.23–2.54), higher overall psychopathological severity (Clinician-Rated Dimensions of Psychosis Symptom Severity [CRDPSS] total score; AOR = 1.56, 95% CI: 1.48–1.66),sleep insufficiency (AOR = 1.79, 95% CI: 1.53–2.10), insufficient dietary status(AOR = 2.00, 95% CI: 1.45–2.81),family history of psychiatric disorders (AOR = 1.38, 95% CI: 1.02–1.88),comorbid physical illnesses (AOR = 1.22, 95% CI: 1.09–1.37),adverse drug reactions (AOR = 1.44, 95% CI: 1.20–1.74),psychiatric follow-up (AOR = 1.36,95% CI:1.17–1.59) and illness stigma (AOR = 1.17, 95% CI:1.03–1.32).Additionally, several factors were associated with decreased odds of social dysfunction,including younger age (18–34 years vs.[Formula: see text] years, AOR = 0.75, 95% CI: 0.58–0.97), being married (AOR = 0.40, 95% CI: 0.32–0.50), retired status (AOR = 0.62, 95% CI: 0.54–0.71), and high life satisfaction (AOR = 0.41, 95% CI: 0.24–0.67).

conclusionSocial dysfunction is highly prevalent among community BD patients. Functional recovery efforts should focus on optimizing pharmacotherapy (to minimize side effects), targeting biological rhythms (sleep and nutrition), enhancing marital and psychosocial support, and improving life satisfaction. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Bipolar DisorderAdultChinaCross-Sectional StudiesFemaleHumansIndependent LivingMaleMiddle AgedPrevalenceYoung AdultAdverse drug reactionsBipolar disorderCommunity-Dwelling patientsSocial dysfunction

Identifiers

PMID41555293
PMCPMC12895624

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