Evidence map›Paper›PMID 41555255›Full record

ArticleBMC anesthesiology2026

Advanced bilateral EEG monitoring for neuroprotection in high-risk cardiac surgery: a successful case report of emergency ascending aortic replacement.

Lorenza Dalla Massara, Michele Carron

Abstract readCase Reports
In one paragraph

Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lorenza Dalla MassaraDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy. lorenza.dallamassara@phd.unipd.it.
Michele CarronDepartment of Medicine - DIMED, Section of Anesthesiology and Intensive Care, University of Padua, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAortic surgery involving circulatory arrest and unilateral cerebral perfusion may be associated with hemispheric differences in scalp-recorded electroencephalographic (EEG) activity that are not detected by standard intraoperative monitoring. Bilateral frontal EEG analysis may provide additional descriptive information on cerebral electrical patterns during these procedures. CASE PRESENTATION: A 62-year-old woman underwent emergency repair for type A aortic dissection with selective right-sided antegrade cerebral perfusion under deep hypothermia. Bilateral frontal EEG monitoring showed a marked reduction in EEG activity during circulatory arrest. Post hoc quantitative spectral analysis revealed asymmetric broadband power changes between hemispheres during cooling and perfusion phases, with alpha/delta ratio (ADR) values decreasing below 0.2 bilaterally and a peak left-to-right ADR ratio of 2.3. These hemispheric spectral differences were not appreciable on raw EEG inspection or cerebral oximetry alone.

conclusionsPost hoc quantitative bilateral EEG analysis, particularly spectral power distribution and ADR trends, may reveal hemispheric differences in scalp-recorded EEG activity during aortic surgery that are not captured by standard monitoring techniques. These observations support the exploratory role of advanced EEG analysis in the intraoperative assessment of cerebral electrical activity under deep hypothermia and selective cerebral perfusion.

Indexed as

AortaCardiac Surgical ProceduresElectroencephalographyMonitoring, IntraoperativeCerebrovascular CirculationCirculatory Arrest, Deep Hypothermia InducedDissection, Ascending AortaFemaleHumansMiddle AgedAlpha/delta ratioAnesthesia, generalAortic surgeryBrain monitoringCerebral perfusionElectroencephalographyHypothermia

Identifiers

PMID41555255
PMCPMC12896048

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.