Evidence map›Paper›PMID 41555238›Full record

ArticleBMC plant biology2026

Integrating GWAS and gene expression to decipher genetic components of pericarp thickness and soluble sugars in sweet corn.

Humera Ashraf, Yu Wu, Yingni Xiao, Xinyue Liang, Xiaofeng Li, Sajid Shokat, Yuliang Li

Abstract read
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Humera Ashraf *Crop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Yu Wu *Crop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Yingni XiaoCrop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Xinyue LiangCrop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Xiaofeng LiCrop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Sajid ShokatWheat Breeding Group, Plant Breeding and Genetics Division, Nuclear Institute for Agriculture and Biology, Faisalabad, 38000, Pakistan.
Yuliang LiCrop Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. yl.lee@126.com.

Funding

Oversea Renowned Teacher Project of Guangdong Province (2022-232-48)This research was supported by the Key Area Research and Development Program of Guangzhou (2023B03J1318)
6 · The paper itself

Abstract

backgroundGrain quality in sweet corn (Zea mays L.) is primarily determined by pericarp thickness and soluble sugar composition, which influence consumer preference and processing suitability. Despite their importance, the genetic basis of these traits remains insufficiently understood. Elucidating the underlying genetic architecture is essential for developing sweet corn varieties with improved kernel texture and sweetness.

resultsA panel of 240 sweet corn inbred lines was evaluated across two seasons in Guangzhou, China, using an alpha-lattice design with two replications to enhance phenotypic precision. Phenotypic data for pericarp thickness and sugar-related traits were adjusted using best linear unbiased predictions (BLUPs), and genotyping was performed with a 60 K SNP array. Genome-wide association study (GWAS) identified 174 loci significantly associated with the target traits, of which 84 were consistently detected across both seasons. Candidate genes within these loci were enriched in biological pathways related to cell wall biosynthesis and sugar metabolism. Notable gene families included cellulose synthase, pectin methylesterase, peroxidase, sucrose synthase, sucrose phosphate synthase, and SWEET transporters, all of which are known to contribute to pericarp development or sugar accumulation. Expression profiling of 12 representative candidate genes in contrasting inbred lines revealed consistent differential expression patterns aligned with phenotypic variation, further supporting their role in regulating pericarp thickness and sweetness.

conclusionsThis study provides a comprehensive analysis of the genetic determinants of grain quality traits in sweet corn. The discovery of stable loci and functionally relevant candidate genes offers new insights into the molecular mechanisms governing kernel texture and sugar accumulation. These findings supply valuable markers and genomic resources for marker-assisted selection and genomic prediction, facilitating the development of improved sweet corn varieties with enhanced quality attributes.

Indexed as

SugarsZea maysEdible GrainGenome-Wide Association StudyGenotypePhenotypePolymorphism, Single NucleotideQuantitative Trait LociSugarsCandidate geneGWASMarker-assisted selectionPericarp thicknessSoluble sugarSweet corn

Identifiers

PMID41555238
PMCPMC12895958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.