Evidence map›Paper›PMID 41555010›Full record

Trial reportLeukemia2026

Treatment-free remission after two nilotinib consolidation durations in chronic myeloid leukemia treated with imatinib: Phase 3 ENESTPath results.

Delphine Rea, Slawomira Kyrcz-Krzemien, Paolo Sportoletti, Jiří Mayer, Arpad Illes, Anna Angona Figueras, Alexander Kiani, Aude Charbonnier, Theodoros Marinakis, Leif Stenke and 6 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IIIMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Leukemia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Delphine ReaService d'Hématologie Adulte, Hôpital Saint-Louis APHP, Paris, France. delphine.rea@aphp.fr.ORCID 0000-0001-5379-7461
Slawomira Kyrcz-KrzemienDepartment of Hematology and BMT, Silesian Medical University Hospital SPSKM, Katowice, Poland.
Paolo SportolettiDepartment of Medicine and Surgery, Institute of Hematology and Center for Hemato-Oncological Research, University of Perugia, Perugia, Italy.
Jiří MayerDepartment of Internal Medicine, Hematology and Oncology, Masaryk University and University Hospital, Brno, Czechia.ORCID 0000-0003-0567-9887
Arpad IllesDepartment of Hematology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Anna Angona FiguerasHospital Josep Trueta - Institut Català d'Oncologia, Girona, Spain.
Alexander KianiDepartment of Medicine IV, Klinikum Bayreuth GmbH, Bayreuth, and Comprehensive Center Erlangen EMN, Erlangen, Germany.ORCID 0000-0002-2494-4087
Aude CharbonnierDepartement d'Hematologie, Institut Paoli Calmettes, Marseille, France.ORCID 0000-0003-0986-9530
Theodoros MarinakisDepartment of Clinical Hematology, G. Gennimatas Hospital, Athens, Greece.
Leif StenkeHematology Center, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
Juan Luis SteegmannHospital de La Princesa, Madrid, Spain.ORCID 0000-0002-7799-5355
Giuseppe SaglioDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-1046-3514
Andrzej HellmannDepartment of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland.
Dietger NiederwieserUniversity of Leipzig, Leipzig, Germany.ORCID 0000-0002-4737-1103
Peter SchuldNovartis Pharma AG, Basel, Switzerland.
Gianantonio RostiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS "Dino Amadori", Meldola, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phase 3 ENESTPath study investigated treatment-free remission (TFR) rates in patients with chronic Philadelphia chromosome-positive (Ph+) and/or BCR::ABL1

Indexed as

Antineoplastic AgentsImatinib MesylateLeukemia, Myelogenous, Chronic, BCR-ABL PositivePyrimidinesAdolescentAdultAgedAged, 80 and overConsolidation ChemotherapyFemaleFusion Proteins, bcr-ablHumansMaleMiddle AgedProtein Kinase InhibitorsRemission InductionAntineoplastic AgentsFusion Proteins, bcr-ablImatinib MesylatenilotinibProtein Kinase InhibitorsPyrimidines

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.