ArticleScientific reports2026
Mustard derived compounds as insecticides and modulators of human metabolism.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
The current investigation aims to decipher the comparative anti-feeding and insecticidal potential of the purified form of Allyl isothiocyanate (AITC), a byproduct of glucosinolate hydrolysis, and three different mustard oils (black, brown and white) against Aulacophora foveicollis (red pumpkin beetle) adults and Spodoptera litura (tobacco cutworm) larvae. The in silico investigation undertakes the interaction of AITC with two anti-oxidant enzymes found in vertebrates, as AITC is also known to be an anti-oxidant and anti-cancerous compound for humans. The study also explores the AITC and protein-protein interaction among pepsin and mustard seed proteins, cruciferin and napin, as mustard contains abundant protein content but remains bio-unavailable due to presence of similar anti-nutritional factors like glucosinolates potentially having insect deterring potential. Through in vitro bioassays, it was found that the AITC was having higher insect anti-feeding potential (ranging from 74.63 to 88.22%) than the three mustard oils (ranging from 40.18 to 78.92%) against two insect pests studied in present investigation. The brown mustard oil showed LC
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