Evidence map›Paper›PMID 41554752›Full record

ArticleNature communications2026

In-memory analog computing for non-negative matrix factorization.

Shiqing Wang, Yubiao Luo, Pushen Zuo, Yongxiang Li, Lunshuai Pan, Daniele Ielmini, Zhong Sun

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shiqing Wang *Institute for Artificial Intelligence, Peking University, Beijing, China.
Yubiao Luo *Institute for Artificial Intelligence, Peking University, Beijing, China.
Pushen ZuoInstitute for Artificial Intelligence, Peking University, Beijing, China.
Yongxiang LiInstitute for Artificial Intelligence, Peking University, Beijing, China.
Lunshuai PanInstitute for Artificial Intelligence, Peking University, Beijing, China.
Daniele IelminiDipartimento di Elettronica e Informazione and IU.NET, Politecnico di Milano, Milano, Italy.ORCID http://orcid.org/0000-0002-1853-1614
Zhong SunInstitute for Artificial Intelligence, Peking University, Beijing, China. zhong.sun@pku.edu.cn.ORCID http://orcid.org/0000-0003-1856-0279

Funding

Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 4252016
6 · The paper itself

Abstract

Non-negative matrix factorization (NMF) is a powerful technique for extracting latent structures from high-dimensional data, with applications spanning recommender systems, bioinformatics, and image processing. However, conventional digital hardware struggles to efficiently handle large-scale NMF due to computational complexity and memory bottlenecks. In this work, we propose an in-memory analog NMF solver based on a reconfigurable compact generalized inverse circuit, optimized using the conductance compensation principle. This circuit significantly reduces power consumption by minimizing the number of operational amplifiers while supporting various non-negative regression constraints. By integrating the alternating non-negative least squares algorithm, we achieve efficient and accurate factorization with a limited number of iterations. Experimental validation demonstrates the effectiveness of our analog NMF solver in real-world tasks, including image compression and collaborative filtering-based recommender systems, achieving high accuracy with orders-of-magnitude improvements in speed and energy efficiency over FPGA- and GPU-based digital solvers. These results highlight the potential of analog matrix computing for enabling real-time, large-scale NMF applications.

Identifiers

PMID41554752
PMCPMC12923777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.