Evidence map›Paper›PMID 41553964›Full record

ArticleNeuroepidemiology2026

Changes in Healthcare Utilization Patterns and Outcomes for an Acute Cerebrovascular Events Medicare Cohort: 2018-2022.

Osvaldo J Laurido-Soto, R J Waken, Fengxian Wang, E John Orav, Rishi K Wadhera, Jose F Figueroa, Susan Searles Nielsen, Ganesh M Babulal, Brad A Racette, Karen E Joynt Maddox

Abstract read
In one paragraph

Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Osvaldo J Laurido-SotoDepartment of Neurology, Washington University School of Medicine, Saint Louis, Missouri, USA, ojlaurido-soto@wustl.edu.
R J WakenCenter for Advancing Health Services, Policy and Economics Research, Washington University, Saint Louis, Missouri, USA.
Fengxian WangCenter for Advancing Health Services, Policy and Economics Research, Washington University, Saint Louis, Missouri, USA.
E John OravDivision of General Internal Medicine and Primary Care, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Rishi K WadheraRichard A. and Susan F. Smith Center for Outcomes Research, Boston, Massachusetts, USA.
Jose F FigueroaDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Susan Searles NielsenDepartment of Neurology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Ganesh M BabulalDepartment of Neurology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Brad A RacetteDepartment of Neurology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Karen E Joynt MaddoxCenter for Advancing Health Services, Policy and Economics Research, Washington University, Saint Louis, Missouri, USA.

Funding

The Health & Aging Brain Study - Health Disparities (HABS-HD)U19AG078109 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI Sid E O'Bryant · 2022 to 2026
$181.1M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Naturalistic driving as a functional neurobehavioral marker of preclinical and symptomatic Alzheimer diseaseR01AG068183 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$6.7M
The impact of bilingualism on cognitive reserve/resilience using socio-demographically and linguistically diverse populationsR01AG080469 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Suvarna Alladi, Ganesh M Babulal · 2023 to 2026
$4.0M
The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older AdultsR01AG067428 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$4.0M
Cardiovascular Health of Low-Income Working-Age Adults in the US: Health Care Access, Policy, and the PandemicR01HL164561 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2022 to 2026
$3.7M
Aging Research Characterizing Health Exposome via Social drivers (ARCHES)R01AG074302 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2021 to 2025
$3.7M
The Impact of Bundled Payments for Cardiopulmonary Disease on High-Risk PopulationsR01HL143421 · NHLBI · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2019 to 2022
$3.1M
The Impact of the ACO REACH Program on Health Outcomes for Patients with Alzheimer's Disease and Related DementiasR01AG089215 · NIA · WASHINGTON UNIVERSITY · PI Karen Ellen Joynt Maddox · 2024 to 2026
$2.1M
Leveraging SNAP Policies to Improve the Cardiovascular Health of Low-Income Adults in the United StatesR01NR021686 · NINR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2024 to 2026
$2.0M
Rural-Urban Disparities In Spillover Effects of COVID-19U01NR020555 · NINR · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2022 to 2024
$1.5M
NCATS NIH HHS KL2 TR002346NCATS NIH HHS UL1 TR002345NHLBI NIH HHS R01 HL143421NHLBI NIH HHS R01 HL164561NIA NIH HHS R01 AG063759NIA NIH HHS R01 AG067428NIA NIH HHS R01 AG068183NIA NIH HHS R01 AG074302NIA NIH HHS R01 AG080469NIA NIH HHS R01 AG089215NIA NIH HHS R01 AG089700NIA NIH HHS R21 AG065526NIA NIH HHS R43 AG087803NIA NIH HHS U19 AG078109NIA NIH HHS UH2 AG083186NINR NIH HHS R01 NR021686NINR NIH HHS U01 NR020555
6 · The paper itself

Abstract

introductionThe coronavirus 2019 pandemic disrupted medical care delivery for cerebrovascular disease. Little is known about the long-term changes in healthcare utilization and mortality among people who suffered cerebrovascular events.

methodsWe used 2018-2022 data to identify all Medicare fee-for-service and Medicare Advantage beneficiaries with a diagnosis code for an acute cerebrovascular event (stroke, transient ischemic attack, hemorrhage). We used Poisson-lognormal regression models with an offset term (beneficiary years) to model incident rate ratios (IRR) for late COVID (2021-2022) versus pre-COVID (2018-2019) for outpatient visits, emergency department (ED) visits, hospitalizations, and mortality in the year following the index event, adjusting for age, sex, and race. We examined patterns overall and by rurality (urban, micropolitan, rural) and quartile (q) of social vulnerability index.

resultsWe identified 7,071,072 and 7,065,171 unique beneficiaries in the pre-COVID and late-COVID periods, respectively, with an acute cerebrovascular event. Our cohort was predominantly non-Hispanic white (73%), female (54%), and urban (83%). Compared to pre-COVID, outpatient care utilization in the year following the acute event was higher in 2021-2022 (IRR = 1.14, 95% confidence interval [CI]: 1.13-1.14), while ED visits (IRR = 0.92, 95% CI: 0.91-0.92) and inpatient hospitalizations (IRR = 0.94, 95% CI: 0.94-0.95) were lower. Mortality was higher during the late-COVID versus pre-COVID period (IRR = 1.24, 95% CI: 1.23-1.25). The mortality differences were similar across rural strata but higher in more socially disadvantaged areas (IRR 1.20, 1.22, 1.24, 1.27 for q1 [reference], p interaction = q2 = 0.12, q3 = 0.01, and q4 < 0.001).

conclusionsMedicare beneficiaries who sustained acute cerebrovascular events had marked differences over the subsequent year in healthcare utilization patterns and increased mortality in the late-COVID period compared with their utilization and outcomes pre-COVID. The differences in mortality were the most pronounced for beneficiaries in socially disadvantaged areas.

Indexed as

HospitalizationMedicareStrokeTransient ischemic attackUtilization

Identifiers

PMID41553964
PMCPMC12863423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.