ArticleFetal diagnosis and therapy2026
The Evolution of Cephalocentesis in Contemporary Obstetric Practice: From Emergency Intervention to Planned Procedure.
Article in Fetal diagnosis and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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15 authors.
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Abstract
<p>Introduction: The aim of the study was to analyze the evolution, indications, and outcomes of cephalocentesis over a 38-year period at two tertiary fetal medicine centers.
methodsA retrospective review of 70 cephalocentesis procedures (1985-2023) was conducted at Mount Sinai Hospital, Toronto, and the National Maternity Hospital, Dublin. Cases were divided into pre-2002 (n = 37) and 2002-onward (n = 33) cohorts in order to evaluate practice evolution.
resultsMean gestational age at diagnosis was 32.7 ± 5.4 weeks with severe hydrocephalus in 95.7% (67/70) and hydranencephaly in 4.3% (3/70) of cases. Pre-2002, 94.6% (35/37) of procedures were performed intrapartum; 2002 onward, this shifted to 66.7% (22/33) pre-labor planned procedures with 84.8% (28/33) using a transabdominal approach. Concurrent fetal analgesia and potassium chloride (KCl) to achieve fetal asystole was introduced in 2002. Vaginal delivery was achieved in 95.7% (67/70) of cases. Perinatal mortality (excluding KCl cases) was 91.8% (45/49). All four survivors (5.8%) demonstrated neurodevelopmental impairment.
conclusionCephalocentesis has evolved from an intrapartum intervention to a planned procedure with standardized protocols. Our findings support reserving this procedure for cases where there is no expectation of postnatal survival, with the primary purpose of facilitating vaginal delivery when caesarean section could unnecessarily increase maternal morbidity. </p>.
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