ArticleAmerican journal of physiology. Heart and circulatory physiology2026
Assessment of impact of low-flow state on long-term outcome in multiethnic population using cardiac magnetic resonance.
Yifang Yuan, Joao A C Lima, David Herrington, James D Thomas, R Brandon Stacey, David Zhao, Mario Garcia, Min Pu
Abstract readMulticenter Study
In one paragraphArticle in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Yifang YuanSection of Cardiology, Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
Joao A C LimaDivision of Cardiology, Johns Hopkins University, Baltimore, Maryland, United States.
David HerringtonSection of Cardiology, Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
James D ThomasDivision of Cardiology, Northwestern University, Evanston, Illinois, United States.
R Brandon StaceySection of Cardiology, Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
David ZhaoSection of Cardiology, Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
Mario GarciaSection of Cardiovascular Imaging, Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, United States.
Min PuSection of Cardiovascular Imaging, Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, United States.ORCID 0000-0002-0076-7186 Funding
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MWake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MSUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTERN01HC95159 · NHLBI · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 2007 to 2014
$19.6MSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC95160 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL · 2007 to 2015
$7.7MSUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC95164 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LIU, KIANG · 2007 to 2015
$7.0MSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC95161 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEA, STEVEN · 2007 to 2014
$6.4MSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC95165 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BURKE, GREGORY L · 2007 to 2014
$6.3MSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC95163 · NHLBI · UNIVERSITY OF MINNESOTA · PI FOLSOM, AARON R · 2007 to 2014
$6.1MTITLE: MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA)N01HC95162 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POST, WENDY · 2007 to 2015
$6.0MSUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC95166 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 2007 to 2014
$4.0MRegional Dysfunction by MRI in Incident Heart FailureR01HL066075 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI LIMA, JOAO A C · 2001 to 2009
$4.0MFoundation for the National Institutes of Health (FNIH) N01-HC-95159Foundation for the National Institutes of Health (FNIH) N01-HC-95160Foundation for the National Institutes of Health (FNIH) N01-HC-95161Foundation for the National Institutes of Health (FNIH) N01-HC-95162Foundation for the National Institutes of Health (FNIH) N01-HC-95163Foundation for the National Institutes of Health (FNIH) N01-HC-95164Foundation for the National Institutes of Health (FNIH) N01-HC-95165Foundation for the National Institutes of Health (FNIH) N01-HC-95166Foundation for the National Institutes of Health (FNIH) N01-HC-95167Foundation for the National Institutes of Health (FNIH) N01-HC-95168Foundation for the National Institutes of Health (FNIH) N01-HC-95169HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1-TR-000040NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NHLBI NIH HHS HHSN268201500003INHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01HC95159NHLBI NIH HHS N01HC95160NHLBI NIH HHS N01HC95161NHLBI NIH HHS N01HC95162NHLBI NIH HHS N01HC95163NHLBI NIH HHS N01HC95164NHLBI NIH HHS N01HC95165NHLBI NIH HHS N01HC95166NHLBI NIH HHS N01HC95167NHLBI NIH HHS N01HC95168NHLBI NIH HHS N01HC95169NHLBI NIH HHS P20 HL101397NHLBI NIH HHS R01 HL066075NIA NIH HHS R01 AG021570
6 · The paper itselfAbstract
Left ventricular (LV) flow state is associated with unfavorable outcome in patient with severe aortic stenosis. However, there is little information on its impact on long-term prognosis in a population without valvular disease. To examine the impact of low-flow state (LFS) on all-cause mortality in multiethnic population, we analyzed 4,398 asymptomatic participants without clinical cardiovascular disease undergoing cardiac magnetic resonance (CMR) in the multiethnic study of atherosclerosis. LV stroke volume index (SVi), LV ejection fraction (LVEF), and myocardial contraction fraction (MCF) were measured. LV flow states were classified as normal flow state (NFS: SVi > 35 mL/m
Indexed as
Cardiovascular DiseasesMagnetic Resonance Imaging, CineVentricular Function, LeftAgedAged, 80 and overFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardial ContractionPredictive Value of TestsPrognosisRisk FactorsStroke VolumeTime Factorscardiac magnetic resonancemortalitystroke volume
Identifiers
PMID41553736
PMCPMC12951615
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