ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2026
Polymorphic light eruption shows aberrant expression of epidermal tight junction proteins in unexposed and UVR-exposed skin: an experimental study.
Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Polymorphic light eruption (PLE) is a common photodermatosis which is believed to be attributable to an immune reaction to an unidentified photoantigen. The epidermal barrier deters skin entry of photoantigens, but its potential contribution to PLE pathogenesis is unexplored. Our objective was to examine the expression of key barrier proteins in PLE patients in vivo compared with healthy controls, both at baseline and after ultraviolet radiation (UVR) exposure. Seven PLE patients and 10 healthy volunteers were recruited. Small areas of buttock skin were exposed to 80 mJ/cm
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