Evidence map›Paper›PMID 41553663›Full record

ReviewThe protein journal2026

Non-specific Protein and Peptide Antibacterial Factors of Mammals.

Pavel Levashov, Ilia Zaitsev, Sergei Zaitsev, Daria Gasanova

Abstract readReview
PubMed Publisher
In one paragraph

Review in The protein journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pavel LevashovDepartment of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia, 119991. levashov@yahoo.com.ORCID http://orcid.org/0000-0002-6821-8888
Ilia ZaitsevDepartment of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia, 119991.
Sergei ZaitsevFederal Research Center for Animal Husbandry Named After Academy Member L.K. Ernst, Dubrovitsy 60, Podolsk Municipal District, Podolsk, Moscow Region, Russia, 142132.
Daria GasanovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia, 119991.

Funding

Russian Science Foundation 25-26-00144
6 · The paper itself

Abstract

The review summarises the basic information on non-specific factors of mammals that potentially have antimicrobial action. A comparison of previously known factors with the latest literature data is carried out. The following peptide and protein factors are considered: lysozymes, transferrins, interferons, interleukin-2, antimicrobial peptides (defensins, cathelicidins, histatins) and protective glycoproteins (mucins, lectins). These major antibacterial factors perform regulatory functions in the immune system, and some are also able to resist viral and fungal infections or oncological pathologies. The study of the internal antibacterial factors of mammals and the mechanisms of their activation is of great importance for the fight against bacterial infections, including antibiotic-resistant ones. This knowledge is necessary for the development of new approaches to the treatment of humans and farm animals.

Indexed as

Anti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesMammalsAnimalsGlycoproteinsHumansInterferonsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesGlycoproteinsInterferonsAntimicrobial peptidesInterferonInterleukin-2LysozymeProtective glycoproteinsTransferrin

Identifiers

PMID41553663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.