ArticleSurgery today2026
Risk factors for 30-day mortality following major neonatal surgery: insights from a 10-year cohort in southern Tunisia.
Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to identify the risk factors for 30-day mortality following neonatal surgery for major thoracic and abdominal conditions.
methodsWe conducted a retrospective cohort study of neonates who underwent major noncardiac abdominal or thoracic surgery in a tertiary pediatric surgery center in Tunisia between April 2015 and March 2025.
resultsA total of 361 neonates underwent major abdominal or thoracic surgeries during the study period. The male-to-female ratio was 1.3:1. The most common surgical conditions were esophageal atresia (n = 105), duodenal atresia (n = 42), and anorectal malformation (n = 39). A total of 85 neonates (23.5%) died within 30 days of surgery. According to a multivariate logistic regression analysis, five variables were independently associated with 30-day mortality.
conclusionThis study demonstrated that an outborn status, prematurity, congenital heart disease, low 5-minute Apgar score, and prolonged operative time predict 30-day mortality after major neonatal surgery. These factors could serve as valuable tools for identifying patients at increased risk and enhancing the quality of their management.
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