Evidence map›Paper›PMID 41553299›Full record

ArticleStatistical methods in medical research2026

A permutation test of differences between externally or internally defined groupings in compositional data sets.

Nikola Štefelová, Javier Palarea-Albaladejo, Josep Antoni Martín-Fernández

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Article in Statistical methods in medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Nikola ŠtefelováDepartment of Computer Science, Applied Mathematics and Statistics, University of Girona, Spain.ORCID 0000-0001-8810-694X
Javier Palarea-AlbaladejoDepartment of Computer Science, Applied Mathematics and Statistics, University of Girona, Spain.ORCID 0000-0003-0162-669X
Josep Antoni Martín-FernándezDepartment of Computer Science, Applied Mathematics and Statistics, University of Girona, Spain.ORCID 0000-0003-2366-1592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testing group differences in compositional data, that is, multivariate data referring to parts of a whole, requires focussing on the relative information between components. This is commonly achieved by mapping the data into a sensible logratio coordinate system. Groupings are often defined by an externally given factor but can also emerge from internal features of the data, such as distinct zero patterns, which may reflect an underlaying structure of subpopulations. This work introduces the PERLOG test, a novel non-parametric permutation test to identify significant groupings based on pairwise logratios, the fundamental units of compositional information. The method is suitable for both externally and internally defined groupings. In particular, the case of groups defined according to zero patterns is discussed as a prominent example of the latter. The performance of the proposal as a statistical test and its advantages over conventional multivariate tests are demonstrated through simulation. Real-world applications are illustrated using data from studies on movement behaviours and time-use epidemiology.

Indexed as

Data Interpretation, StatisticalComputer SimulationModels, StatisticalMultivariate AnalysisStatistics, Nonparametriccompositional dataGroup comparisonspairwise logratiospermutation testtime-use epidemiologyzeros

Identifiers

PMID41553299
PMCPMC13047227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.