Evidence map›Paper›PMID 41553029›Full record

ArticleJournal of oral rehabilitation2026

Comparative Analysis of Oral Hypofunction in Community-Dwelling Adults in Japan and Clinic-Recruited Community-Dwelling Adults in Switzerland: A Cross-Sectional Study.

Risako Mikami, Matsuo Koichiro, Lisa Takeshita, Misaki Tanaka, Claudio Rodrigues Leles, Dusit Nantanapiboon, Rena Hidaka, Manabu Kanazawa, Murali Srinivasan

Abstract readComparative Study
In one paragraph

Article in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Risako MikamiDepartment of Advanced Biomaterials, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-1398-0450
Matsuo KoichiroDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Lisa TakeshitaClinic of General, Special Care and Geriatric Dentistry, Center for Dental Medicine, University of Zürich, Zurich, Switzerland.
Misaki TanakaDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Claudio Rodrigues LelesClinic of General, Special Care and Geriatric Dentistry, Center for Dental Medicine, University of Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-6812-4849
Dusit NantanapiboonClinic of General, Special Care and Geriatric Dentistry, Center for Dental Medicine, University of Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-6170-5053
Rena HidakaDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Manabu KanazawaDepartment of Gerodontology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Murali SrinivasanClinic of General, Special Care and Geriatric Dentistry, Center for Dental Medicine, University of Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3365-576X

Funding

GC CorporationGC international
6 · The paper itself

Abstract

backgroundOral hypofunction (OHF) is a multidimensional condition representing a subclinical decline in oral function. Cross-national comparisons using standardised criteria remain limited.

objectivesThis study aimed to compare the prevalence and characteristics of OHF among community-dwelling adults in Japan and Switzerland and to examine age-related patterns using standardised assessments.

methodsA cross-sectional study was conducted in community settings in Japan (153 participants) and in a university dental clinic in Switzerland (117 participants). OHF assessments were performed between May 2023 and January 2024 in Japan and between December 2023 and January 2024 in Switzerland. Data were collected by trained and calibrated examiners from both countries following standardised protocols. OHF was diagnosed when three or more of the seven oral function domains, including oral hygiene, oral dryness, occlusal force, tongue-lip motor function, tongue pressure, masticatory function, and swallowing function, were impaired. Multiple logistic regression analyses were performed with OHF as the outcome after adjusting for country, age, and covariates. Interactions between country and age were also investigated.

resultsThe prevalence of OHF was 30.7% in Japanese participants and 49.6% in Swiss participants (p = 0.002). The Swiss participants demonstrated significantly better oral hygiene (p < 0.001), while the Japanese participants showed better tongue pressure (p = 0.026), lip-tongue motor function (p < 0.001), maximum occlusal force (p = 0.002), and masticatory function (p < 0.001). In logistic regression, OHF was associated with Swiss nationality (odds ratio [OR]: 3.85, 95% confidence interval [CI]: 1.85-8.00, p < 0.001), age ≥ 70 years (OR: 5.73, 95% CI: 1.67-19.68, p = 0.006, compared to those in their 20s), lower hand grip strength (OR: 0.91, 95% CI: 0.87-0.96, p = 0.001), and fewer teeth (OR: 0.94, 95% CI: 0.89-0.98, p = 0.008). A significant interaction between country and age indicated differing age-related OHF progression between the Japanese and Swiss populations.

conclusionBoth populations exhibited age-related declines in oral function; however, functional impairment was more prevalent and progressive in Switzerland. These findings support the cross-cultural applicability of the OHF criteria and underscore the need for population-specific preventive strategies.

Indexed as

Independent LivingXerostomiaAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansJapanMaleMasticationMiddle AgedOral HealthOral HygienePrevalenceSwitzerlandagingdeglutition disordersgeriatric dentistrymastication disordersstomatognathic diseases

Identifiers

PMID41553029
PMCPMC13053601

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.