Evidence map›Paper›PMID 41552947›Full record

SynthesisHead & neck2026

Obstructive Sleep Apnea Following Head and Neck Chemoradiation: A Scoping Review With Exploratory Meta-Analysis.

Augustin G L Vannier, Neil S Kondamuri, Megan S Wu, Janya Allen, Nihar Rama, Rachel Nordgren, Nishant Agrawal, Phillip S LoSavio

Abstract readMeta-AnalysisScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Augustin G L VannierPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.
Neil S KondamuriDepartment of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, Illinois, USA.
Megan S WuDepartment of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, Illinois, USA.
Janya AllenUniversity of Chicago, Chicago, Illinois, USA.
Nihar RamaPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.
Rachel NordgrenDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-3664-1208
Nishant AgrawalDepartment of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, Illinois, USA.
Phillip S LoSavioDepartment of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0001-7242-4943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnea (OSA) may contribute to fatigue in head and neck cancer patients undergoing chemotherapy and radiotherapy, particularly as both have the potential to impact the mechanics and dynamics of the airway. We conducted a scoping review and exploratory meta-analysis to evaluate the risk of OSA following chemoradiation.

methodsPubMed, Web of Science, EMBASE, and Cochrane Library were searched for studies assessing incident OSA after radiotherapy or chemotherapy. Eligible studies isolated the effect of one treatment and reported OSA rates in each group.

resultsOf 559 papers identified, 110 were duplicates and 30 underwent full-text review; 13 met criteria for exploratory meta-analysis. A modest, nonsignificant trend toward increased risk of mild OSA was observed with radiotherapy (z = 1.42, p = 0.15). Chemotherapy was not associated with mild (z = -0.83, p = 0.41) or moderate (z = 0.00, p = 1.00) OSA.

conclusionsStudies are limited in size and number, and do not support increased risk of OSA with radiotherapy.

Indexed as

ChemoradiotherapyHead and Neck NeoplasmsSleep Apnea, ObstructiveFemaleHumansMalecancerchemotherapyobstructive sleep apnearadiotherapy

Identifiers

PMID41552947
PMCPMC13155189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.