ArticleJournal of surgical case reports2026
Acute bilateral ureteric obstruction after Deflux injection: a case report.
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Vesicoureteral reflux (VUR) is a prevalent cause of recurrent urinary tract infections and renal scarring in pediatric patients, managed with conservative measures or surgical intervention. Endoscopic sub-ureteral bulking agent injection provides a minimally invasive option. We present a 7-year-old boy with severe bilateral VUR who developed acute bilateral ureteral obstruction following dextranomer/hyaluronic acid (Deflux) injection. Despite an unremarkable early postoperative course, he developed severe abdominal pain, vomiting, anuria, elevated creatinine, and worsening hydronephrosis. Emergency cystoscopy with bilateral double-J stent placement relieved the obstruction. Significant inflammatory masses at the uretero-vesical junction markedly improved following stent removal. The patient remained asymptomatic without hydronephrosis after 5 years. This case highlights the uncommon but significant risk of ureteral obstruction following endoscopic bulking agent injection and emphasizes the need for careful post-procedural monitoring.
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