Evidence map›Paper›PMID 41552594›Full record

ArticleACS omega2026

Biophysical Characterization and Structural Insights Into the Complex between the Extracytoplasmic Function Sigma Factor, PupI, with the Antisigma Domain of the Sigma Regulator, PupR, from

Tajnin Sultana, Robin N Kutsi, Alexander Tischer, Siri Froiland, Elizabeth L Gertz, Jaime L Jensen, Matthew Auton, Sangita C Sinha, Christopher L Colbert

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tajnin SultanaDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
Robin N KutsiDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
Alexander TischerDivision of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, United States.
Siri FroilandDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
Elizabeth L GertzDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
Jaime L JensenDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.ORCID https://orcid.org/0000-0002-8818-7513
Matthew AutonDivision of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, United States.ORCID https://orcid.org/0000-0002-4446-6932
Sangita C SinhaDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.ORCID https://orcid.org/0000-0003-0953-4263
Christopher L ColbertDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.ORCID https://orcid.org/0000-0001-9577-9544

Funding

Structure-Resolved Mechanistic Phenotyping of Von Willebrand DiseaseR01HL146508 · NHLBI · MAYO CLINIC ROCHESTER · PI AUTON, MATTHEW · 2020 to 2023
$1.9M
Structural basis of sigma-regulator recognition by a site-1 protease during cell surface signaling by Gram-negative bacteria.R01GM126207 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI Christopher L Colbert · 2018 to 2026
$1.7M
Sigma-regulator recognition and activation of regulated intramembrane proteolysis by a site-1 protease during iron import cell surface signaling in Gram-negative bacteria.R15GM160942 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI COLBERT, CHRISTOPHER L · 2025 to 2025
$544k
Molecular mechanism by which Epstein-Barr Virus-encoded BHRF1 blocks BECN1-mediated autophagyR15GM146232 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI HERSHBERGER, JOHN F · 2022 to 2023
$535k
NHLBI NIH HHS R01 HL146508NIGMS NIH HHS R01 GM126207NIGMS NIH HHS R15 GM146232NIGMS NIH HHS R15 GM160942
6 · The paper itself

Abstract

Gram-negative bacteria utilize siderophores to scavenge for environmental iron.

Identifiers

PMID41552594
PMCPMC12809585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.