ArticleACS omega2026
Development of a Gelatin-Based Composite Hydrogel Powder with Kaolin and Sr-Doped Hydroxyapatite for Dual Hemostatic and Osteogenic Potential.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective management of postextraction wounds requires biomaterials that can simultaneously achieve rapid hemostasis and promote bone regeneration. This study aims to develop a multifunctional hydrogel powder incorporating gelatin (Gel), oxidized dextran (ODex), kaolin (KC), and strontium-doped hydroxyapatite (Sr-HA) for synergistic hemostatic and osteoinductive effects. Sr-HA was synthesized and characterized using FTIR, XRD, TEM, and XPS to confirm successful strontium incorporation. Gel/ODex-based composite hydrogels were prepared via Schiff base cross-linking, and their rheological properties, swelling behavior, degradation profiles, and microstructure were systematically evaluated. Hemostatic performance was assessed using rat liver and tail amputation models. Cytocompatibility and osteogenic potential were examined through cell viability assays, ALP and ARS staining, and expression analysis of osteogenesis-related genes and proteins via RT-qPCR and Western blotting. Sr-HA exhibited enhanced crystallinity and chemical integration within the crystalline structure of HA. The Gel/ODex/KC/Sr-HA hydrogel showed improved mechanical strength, controlled degradation, and a porous microstructure.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.