Evidence map›Paper›PMID 41552444›Full record

ArticleACS omega2026

Bioactivity and Biocompatibility of a Polydopamine-Bridged, BMP-2-Functionalized Multilayer Coating on Stainless Steel for Bone Implant Applications.

Muhammad Khari Secario, Hsin-Hsin Yu, Dave W Chen, Jui-Yang Lai, Thi Tuong Vi Truong, Chien-Chang Chen, Shingjiang Jessie Lue

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad Khari SecarioDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan City 333, Taiwan.ORCID https://orcid.org/0000-0003-1271-3588
Hsin-Hsin YuDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan City 333, Taiwan.
Dave W ChenDepartment of Orthopedic Surgery, Chang Gung Memorial Hospital, Keelung City 204, Taiwan.
Jui-Yang LaiDepartment of Biomedical Engineering, Chang Gung University, Taoyuan City 333, Taiwan.ORCID https://orcid.org/0000-0002-9227-8549
Thi Tuong Vi TruongDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan City 333, Taiwan.
Chien-Chang ChenDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, Taoyuan City 333, Taiwan.
Shingjiang Jessie LueDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan City 333, Taiwan.ORCID https://orcid.org/0000-0003-1950-8093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implant failure due to poor osteogenesis and bacterial infection remains a major concern, emphasizing the importance of enhancing both the osteogenic and antibacterial activities of implants. This study focuses on using polydopamine (PDA)-bridged bone morphogenetic protein-2 (BMP2) and grafting it onto benzophenone (BP)-photoinitiated 2-methacryloyloxyethyl phosphorylcholine (MPC)-coated stainless steel (SS) to form a functionalized SS substrate (SS-BP-MPC-PDA-BMP2). The PDA bridge layer induced a greater BMP2 immobilization level (6-fold improvement), mitigated burst release, and sustained a controlled release rate (0.44 ng/cm

Identifiers

PMID41552444
PMCPMC12809520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.