ArticleAmerican journal of translational research2025
Syringe-assisted aspiration combined with mechanical aspiration thrombectomy effectively alleviates lower extremity deep vein thrombosis.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate the safety and efficacy of syringe-assisted aspiration combined with mechanical aspiration thrombectomy in the management of lower-extremity deep vein thrombosis (DVT).
methodsA retrospective analysis was conducted on 112 patients with DVT admitted to our hospital between January 2024 and June 2025. Patients were allocated to either the Mechanical Aspiration group (MA group, n = 50) or the Syringe-Assisted Mechanical Aspiration group (SMA group, n = 62). Outcomes compared between the two groups included stent implantation rate, thrombolysis duration and thrombolytic drug dosage, limb swelling rate, thrombus clearance rate, lower-limb circumference difference, venous patency score, Villalta scale for post-thrombotic syndrome, hemodynamic parameters, quality of life, complications, and recurrence.
resultsBaseline characteristics were comparable between the two groups. The SMA group demonstrated a lower stent implantation rate, shorter thrombolysis duration, higher limb deswelling and thrombus clearance rates, and lower urokinase dosage, hospitalization time, and medical costs (P < 0.05). All clinical indicators improved after treatment, with greater improvements observed in the SMA group. No significant differences were found in complication or recurrence rates between the groups (P > 0.05).
conclusionSyringe-assisted aspiration combined with mechanical aspiration thrombectomy is an effective and safe treatment option for lower-extremity DVT. This combined approach can reduce thrombolytic drug requirements and hospitalization costs, enhance hemodynamics and quality of life, and demonstrate a favorable safety profile.
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