ArticleAmerican journal of translational research2025
Effect of Xiangpi Shengji ointment combined with nano-silver medical antibacterial dressing on wound healing of deep partial thickness burn.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundDeep second-degree burn wounds lead to infection, significant inflammation, and delayed healing, with sole dressing therapies exhibiting limited efficacy. This study was to investigate the therapeutic effect of Xiangpi Shengji ointment combined with nano-silver medical antibacterial dressing to provide a clinical reference.
methodsA retrospective analysis was implemented on 115 patients with deep second-degree burns at the First Hospital of Hebei Medical University from February 2023 to August 2025. Patients were rolled into a treatment group (n=59, combination therapy) and a control group (n=56, nano-silver dressing alone). Inflammatory factors, growth factors, infection markers, healing indicators, pain and scar scores, and clinical efficacy were compared between the two groups employing
resultsOn days 7 and 14, IL-16 was lower in the treatment group than that in the control group, while growth factor EGF was higher from day 14 onward (both P<0.05). The treatment group had a lower bacterial positivity rate, lower incidence of fever, shorter eschar separation time, wound healing time, and hospital stay (all P<0.05). Visual Analogue Scale and VSS scores were greatly lower at all post-treatment time points in the treatment group (both P<0.05). The total effective rate was 91.53% in the treatment group, markedly surpassed 71.43% in the control group (all
conclusionThe combined regimen can alleviate inflammation, inhibit infection, promote repair, shorten healing time and hospital stay, improve pain and scar outcomes, and enhance therapeutic efficacy, demonstrating value for clinical application.
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