ArticleIEEE transactions on radiation and plasma medical sciences2025
The Alpha-SPECT-Mini: A Small-Animal SPECT System based on Hyperspectral Compound-Eye Gamma Cameras.
Article in IEEE transactions on radiation and plasma medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Quantitative SPECT imaging ofMedical physics · 2026Article
- Exploring Anti-Coincidence Technique for Scattering Contamination Rejection in a Simultaneous PET/SPECT Imaging System.IEEE transactions on radiation and plasma medical sciences · 2026Article
- Experimental Evaluation of DE-SPECT: A Hyperspectral SPECT System for Region-Selective 3-D Gamma-Ray Spectroscopy.IEEE transactions on radiation and plasma medical sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
There is a rising interest in Single Photon Emission Computed Tomography (SPECT) imaging systems with improved energy resolution to facilitate multi-functional molecular imaging applications, such as alpha-emitter radiopharmaceutical therapy (α-RPT). In this paper, we report the design and evaluation of the Alpha-SPECT-Mini system that offers an ultrahigh energy resolution and high sensitivity for small animal studies. The Alpha-SPECT-Mini system is constructed based on small-pixel CdTe detectors that offers sub-1keV Full-Width-Half-Maximum (FWHM) energy resolution for single pixel events and an average ~2.5keV energy resolution at 122 keV and ~3.5 keV at 218 keV over 153600 pixels in the system. This allows to easily identify X- and gamma-ray contributions in densely populated spectra, such as from the Ac-225 decay chain. The system uses a 96-loft-hole collimator and six stationary detection panels in a full ring geometry. Finally, the system performance is demonstrated using Tc-99m- and Ac-225-filled resolution and image quality (IQ) phantoms. We have experimentally demonstrated that the Alpha-SPECT-Mini is a high-performance imaging system capable of imaging alpha-emitters in preclinical applications.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.