Evidence map›Paper›PMID 41552270›Full record

ArticleFrontiers for young minds2024

Genomic Data: Building Blocks For Life Or Abstract Art?

Rachel Horton, Kate Lyle, Susie Weller, Lisa Ballard, Anneke Lucassen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers for young minds, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel HortonClinical Ethics, Law and Society (CELS), Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Kate LyleClinical Ethics, Law and Society (CELS), Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Susie WellerClinical Ethics, Law and Society (CELS), Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Lisa BallardClinical Ethics, Law and Society (CELS), Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, United Kingdom.
Anneke LucassenClinical Ethics, Law and Society (CELS), Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Funding

Wellcome Trust 208053Wellcome Trust 218092
6 · The paper itself

Abstract

The genes found in the genetic code (genome) are sometimes called the "building blocks for life" but knowing how they impact human health can be more complicated than it sounds. This article aims to show how difficult it can be to understand how our genes can affect our health, and why it is not always easy to work out a patient's result from genetic tests. We follow the story of Ben, whose muscles have been getting weaker for a few years. To find out why, Ben has had his genetic code sequenced, and we will walk you through a process by which his results can be analyzed. Through this activity, we will show you that analyzing patients' genome tests is a bit like interpreting abstract art, in which different people might see and value different things.

Identifiers

PMID41552270
PMCPMC7618640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.