Evidence map›Paper›PMID 41552204›Full record

ArticleCureus2025

Slow-Onset Epidural Anesthesia for Cesarean Delivery in Severe Multivalvular Heart Disease and Atrial Fibrillation: The Role of Preoperative Optimization and Hemodynamic-Guided Management.

Maria Massá Castro, João Gonzalez, Filipa Lança

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Massá CastroAnesthesiology, Unidade Local de Saúde de Santa Maria, Lisbon, PRT.
João GonzalezAnesthesiology, Unidade Local de Saúde de Santa Maria, Lisbon, PRT.
Filipa LançaAnesthesiology, Unidade Local de Saúde de Santa Maria, Lisbon, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy places substantial stress on the cardiovascular system, and this effect is amplified in females with rheumatic valvular disease. We describe the anesthetic management of a 37-year-old multiparous patient with severe multivalvular disease (severe mitral stenosis, severe aortic insufficiency, and severe tricuspid regurgitation with stenosis) and atrial fibrillation, presenting with signs of congestive heart failure, who was submitted to an elective cesarean section at 37 weeks of gestation. Following admission, she received targeted medical optimization in a cardiac intensive care setting, including rate control and diuretic therapy, with subsequent clinical improvement. Anticoagulation with low-molecular-weight heparin was suspended 24 hours before surgery. Considering her fixed cardiac output and the potential harm of abrupt hemodynamic shifts during surgery, a slow-onset epidural anesthesia under invasive monitoring was performed. Incremental boluses of 0.75% ropivacaine, combined with early vasopressor support, allowed for an adequate sensory block, maintaining hemodynamic stability throughout surgery. Intraoperative tachyarrhythmia was managed through cautious fluid administration and pharmacological treatment. Oxytocin was carefully and slowly administered to prevent sudden reductions in systemic vascular resistance. Since resumption of therapeutic anticoagulation was planned due to high thromboembolic risk, the epidural catheter was removed at the end of the surgery. A multimodal analgesic strategy was adopted, including a single epidural morphine bolus and bilateral transversus abdominis plane blocks. Both maternal and neonatal outcomes were favorable. This case highlights the importance of meticulous preoperative optimization and planning, the safety of graded neuraxial anesthesia, and the need for multidisciplinary discussion when managing parturients with advanced multivalvular heart disease.

Indexed as

atrial fibrillationcesarean sectionepidural anesthesiahemorrhagic riskhigh-risk pregnancymaternal cardiac diseasemitral stenosismultiparitymultivalvular diseaserheumatic heart disease

Identifiers

PMID41552204
PMCPMC12812039

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.