Evidence map›Paper›PMID 41552174›Full record

ArticleCureus2025

Bilateral Cerebellopontine Angle Masses in a 72-Year-Old Woman With Prior Malignant Melanoma and a Cochlear Implant: A Diagnostic and Management Challenge.

Syeda Faiza Fatima, Ibidapo Yusuf

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Syeda Faiza FatimaDepartment of Emergency Medicine, North West Anglia NHS Foundation Trust, Peterborough, GBR.
Ibidapo YusufDepartment of Emergency Medicine, North West Anglia NHS Foundation Trust, Peterborough, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebellopontine angle masses are most frequently vestibular schwannomas, but may also represent metastatic disease, particularly in patients with a history of malignant melanoma. We describe the case of a 72-year-old woman with a prior history of melanoma and a right cochlear implant who presented with rapidly progressive bilateral hearing loss, visual impairment, imbalance, and right-sided facial weakness. An initial non-contrast CT scan was reported as normal, although a later multidisciplinary review identified bilateral cerebellopontine angle lesions. MRI, the gold standard for characterising lesions of this region, could not be performed because of the cochlear implant. The differential diagnosis included bilateral vestibular schwannomas and metastatic melanoma. During hospitalisation, the patient developed an infection that resolved with antibiotic therapy but continued to deteriorate neurologically, with worsening visual loss and recurrent falls. A repeat contrast-enhanced CT scan demonstrated enlargement of the cerebellopontine angle lesions with associated cerebral oedema and ventricular dilatation. Her past genetic testing had confirmed BRAF positivity, though her frailty and poor functional status excluded neurosurgical or targeted systemic treatment. Following multidisciplinary and family discussions, palliative care was initiated. The patient experienced progressive decline and died 45 days after admission. This case illustrates the diagnostic and therapeutic challenges associated with bilateral cerebellopontine angle lesions in patients with a history of melanoma when MRI is contraindicated. It highlights the aggressive behaviour of melanoma metastases, the limitations in imaging and treatment options in frail patients with implants, and the importance of involving palliative care early to optimise symptom management and family support.

Indexed as

brain metastasescerebellopontine anglecochlear implantdiagnostic challengemalignant melanomametastatic melanomaneurological deteriorationpalliative carevestibular schwannomavisual loss

Identifiers

PMID41552174
PMCPMC12810755

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.