ArticleCureus2025
Fetomaternal Outcome Among Antenatal Attendees With Advanced Maternal Age: A Cohort Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Advanced maternal age (AMA) has become increasingly prevalent as women postpone childbearing due to social, cultural, and economic reasons. Previous studies have linked AMA to a higher risk of adverse maternal and fetal outcomes, but regional data from Oman remain limited. Objective This study aimed to evaluate the association between AMA and pregnancy outcomes in women attending antenatal visits at Musannah Polyclinic and AR-Rustaq General Hospital. Methodology This observational comparative cohort study was conducted at Musannah Polyclinic, Sultanate of Oman, over 12 months beginning in July 2024. A total of 646 pregnant women were enrolled, comprising 323 women aged ≥40 years (AMA group) and 323 women <35 years (control group). Participants were recruited using non-probability convenience sampling. Data collection included demographic variables, maternal comorbidities, pregnancy complications, and fetal outcomes. Laboratory and imaging assessments were performed according to Ministry of Health protocols. Statistical analysis was conducted using SPSS version 26, with t-tests and chi-square tests applied for group comparisons, and logistic regression performed to identify independent predictors of adverse outcomes. Results The mean age in the AMA group was 42.8 ± 2.1 years versus 28.6 ± 3.5 years in controls (p < 0.001). AMA women had significantly lower spontaneous vaginal delivery rates (52/323; 16.1% vs. 149/323; 46.1%, p < 0.001) and higher preterm delivery rates (14/323; 4.3% vs. 5/323; 1.5%, p = 0.03). Gestational diabetes was significantly higher in AMA women (156/323; 48.3% vs. 47/323; 14.6%, p < 0.001), as were hypertensive disorders (38/323; 11.8% vs. 9/323; 2.8%, p < 0.001) and thyroid disorders (38/323; 11.8% vs. 11/323; 3.4%, p < 0.001). Fetal complications were also increased, including miscarriage (17/323; 5.3% vs. 4/323; 1.2%, p = 0.004) and NICU admissions (11/323; 3.4% vs. 3/323; 0.9%, p = 0.04). Logistic regression confirmed AMA as an independent predictor of gestational diabetes, hypertensive disorders, cesarean delivery, miscarriage, NICU admission, and thyroid disorders. Conclusion AMA is strongly associated with adverse maternal and fetal outcomes, underscoring the need for targeted antenatal monitoring, early screening, and specialized counseling in this high-risk group.
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