ArticleCureus2025
Optimizing Dermal Filler for Chin and Jawline Definition as an Advanced Approach for Natural Results: A Prospective Case Series With Ultrasonographic and 3D Facial Imaging Evaluation.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-surgical mandibular contouring has gained attention as a safe and effective approach to improve jawline aesthetics and restore lower facial definition. This study aimed to assess the efficacy, safety, and patient satisfaction associated with an anatomically guided hyaluronic acid (HA) filler technique designed to enhance chin projection and mandibular contour using minimal product volume. Ten healthy patients aged 25-45 years underwent individualized treatments guided by facial proportions and anatomical landmarks. A maximum of 6 mL of high elastic modulus (G') HA filler was administered per patient. Three-dimensional photographic documentation and ultrasound imaging were used to guide applications and monitor outcomes. The results showed consistent enhancement in lower face definition across all patients, with a 98% satisfaction rate and no major adverse events reported. These findings support the use of this anatomically guided protocol as a reproducible and minimally invasive option for lower facial rejuvenation, offering effective aesthetic improvements while maintaining a favorable safety profile.
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Registered trials
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