Evidence map›Paper›PMID 41551687›Full record

ArticleWorld journal of clinical cases2026

Gallstones and gallbladder wall thickening in patients with cirrhosis: Prevalence and clinical impact.

Alexandra Tsankof, Adonis A Protopapas, Vaia Kyritsi, Christiana Gogou, Maria Kyziroglou, Erofili Papathanasiou, Charikleia Chatzikosma, Aristeidis Michalopoulos, Christos Savopoulos, Andreas N Protopapas

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Article in World journal of clinical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alexandra TsankofFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Adonis A ProtopapasFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece. adoprot@hotmail.com.
Vaia KyritsiFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Christiana GogouFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Maria KyziroglouFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Erofili PapathanasiouFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Charikleia ChatzikosmaFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Aristeidis MichalopoulosFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Christos SavopoulosFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.
Andreas N ProtopapasFirst Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki 54636, Kentrikí Makedonía, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGallstones and gallbladder wall thickening (GBWT) are frequent findings in patients with cirrhosis, reflecting the critical interplay between hepatobiliary dysfunction and portal hypertension.

aimTo assess the prevalence of gallstones and asymptomatic GBWT in patients with cirrhosis.

methodsHospitalized patients with cirrhosis who had undergone abdominal imaging studies during hospitalization were retrospectively analyzed.

resultsA total of 128 patients were included. The patients had a mean age of 64 ± 12.2 years, were predominantly male (73.4%), and most had decompensated liver cirrhosis (DeCi) (78.1%). Alcohol-associated liver disease (47.7%) and metabolic dysfunction-associated steatohepatitis (16.4%) are the leading causes of cirrhosis. Most patients were classified as Child-Pugh stage B (53.1%), followed by stage C (32%), and stage A (14.8%). A significant percentage of patients had cholelithiasis (39.8%), and DeCi patients were more likely to have gallstones (45%) than compensated patients (21.4%) (

conclusionThis study underlines the high prevalence of radiologic gallbladder findings in patients with cirrhosis while simultaneously serving as a reminder to clinicians to refrain from accrediting these findings to a diagnosis of acute cholecystitis in the absence of symptoms.

Indexed as

AsymptomaticCirrhosisDecompensationGallbladderGallstones

Identifiers

PMID41551687
PMCPMC12809154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.