ArticleFrontiers in microbiology2025
Gut microbiota and traumatic brain injury: insights from an antibiotic-free cohort.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Severity-stratified gut microbiome dysbiosis and systemic neuroinflammation in acute traumatic brain injury: a metagenomic and cytokine profiling study.Frontiers in microbiology · 2026Article
- Association between the systemic inflammation response index and serum uric acid in acute traumatic brain injury: a cross-sectional study.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
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Abstract
Introduction: Traumatic brain injury (TBI) is a major global health concern, leading to persistent neurological deficits and systemic complications. While animal studies have shown the association between TBI and the gut microbiota, human evidence, particularly in the early post-injury period, remains scarce. Methods: In this study, we profiled the gut microbiota of TBI patients within 8 days of hospitalization using 16S rRNA sequencing, integrating clinical metadata and excluding individuals who had received antibiotics within the preceding month. Results: Although alpha diversity remained similar between groups, beta diversity was significantly altered in TBI patients relative to healthy controls, accompanied by increased inter-individual variability. Differential abundance analysis revealed a depletion of short-chain fatty acid (SCFA)-producing taxa, e.g., Discussion: Collectively, these findings indicate that TBI is associated with dysbiosis of the gut microbial and altered metabolic potential.
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