Evidence map›Paper›PMID 41551593›Full record

ArticleExtracellular vesicles and circulating nucleic acids2025

5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer.

Haoyu Chen, Tianyu Gao, Hangyu Chen, Lei Zhang, Xianglong Chen, Maimaitiyasen Duolikun, Xiaxuan Li, Xuehui Li, Long Chen, Han Gao and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Extracellular vesicles and circulating nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Haoyu ChenSchool of Graduate, Hebei University of Chinese Medicine, Shijiazhuang 050091, Hebei, China.
Tianyu GaoSchool of Graduate, Hebei University of Chinese Medicine, Shijiazhuang 050091, Hebei, China.
Hangyu ChenDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Lei ZhangDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Xianglong ChenSchool of Information and Intelligent Engineering, University of Sanya, Sanya 572022, Hainan, China.
Maimaitiyasen DuolikunKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570100, Hainan, China.
Xiaxuan LiSchool of Information and Communication Engineering, Hainan University, Haikou 570228, Hainan, China.
Xuehui LiDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Long ChenDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Han GaoDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Qi LiSchool of Graduate, Hebei University of Chinese Medicine, Shijiazhuang 050091, Hebei, China.
Xinyu HaoDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing 100191, China.
Pingping ZhouDepartment of Gastroenterology, Hebei Province Hospital of Chinese Medicine, Shijiazhuang 050011, Hebei, China.
Ningning RenDepartment of Gastroenterology, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing 100029, China.
Jian LinDepartment of Pharmacy, Peking University Third Hospital, Beijing 100191, China.
Yangang WangSchool of Graduate, Hebei University of Chinese Medicine, Shijiazhuang 050091, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-hydroxymethylcytosineextracellular vesicle DNAsmolecular biomarkerPrecancerous lesions of gastric cancer

Identifiers

PMID41551593
PMCPMC12809687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.