ArticleRespirology case reports2026
A Rare Case of Pulmonary Alveolar Proteinosis Superimposed by Severe COVID-19 Pneumonia: Case Report.
Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Rare Case of Pulmonary Alveolar Proteinosis Superimposed by Severe COVID-19 Pneumonia: Case Report.Respirology case reports · 2026Article
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3 authors.
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Abstract
COVID-19 pneumonia is a strong radiological mimicker of pulmonary alveolar proteinosis (PAP), making their differentiation difficult. PAP is a rare diffuse lung disease caused by the accumulation of surfactant lipoproteins within the alveoli, resulting in impaired gas exchange and respiratory failure, with an estimated prevalence of 3.7-6.2 cases per million. This report presents a rare case of PAP complicated by COVID-19 pneumonia in a 42-year-old man who presented with chills, fatigue, dyspnea and fever. Clinical, laboratory and radiological features were thoroughly assessed. High-resolution CT revealed a crazy-paving pattern with patchy consolidations, diffuse ground-glass opacities and septal thickening. Early recognition of lung diseases with overlapping imaging features is essential to guide management and prevent adverse outcomes. The coexistence of PAP and COVID-19 was associated with rapid clinical deterioration and poor prognosis. Further studies are needed to clarify underlying mechanisms and optimise treatment strategies.
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