Evidence map›Paper›PMID 41551502›Full record

ArticleFrontiers in medicine2025

Functional decline after severe COVID-19: duke activity status index for preoperative risk assessment.

Luis Alberto Rodriguez Linares, Sarah Cerillo Lopes

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Luis Alberto Rodriguez LinaresDepartment of Anesthesiology, São Paulo University, São Paulo, Brazil.
Sarah Cerillo LopesDepartment of Anesthesiology, ABC Foundation School of Medicine (FMABC), Santo André, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Survivors of severe COVID-19 (Coronavirus Disease 2019) frequently experience long-term functional impairment, a condition known as post-COVID syndrome. As these patients may eventually undergo surgical procedures, evaluating their functional capacity becomes essential for safe anesthetic management. The Duke Activity Status Index (DASI) is a validated, easy-to-administer tool that correlates with cardiopulmonary fitness and surgical risk. Objective: To evaluate changes in functional capacity using DASI scores in patients who survived severe COVID-19, comparing pre- and post-infection performance, and to assess implications for perioperative care. Methods: A retrospective observational study was conducted including 31 patients with a history of severe COVID-19 requiring ICU (Intensive Care Unit) admission. DASI scores were collected before and after hospitalization due to COVID-19. Associations between DASI variation and clinical variables (e.g., presence of pleural effusion, duration of intubation, ICU stay) were also explored. Results: A marked decline in functional capacity was observed after COVID-19, with lower DASI scores post-infection. The presence of pleural effusion and ultrasound abnormalities were associated with more pronounced reductions in DASI scores. A strong correlation was found between duration of intubation and length of hospital stay, and between post-COVID DASI and percentage variation. Conclusion: Severe COVID-19 has a lasting impact on functional capacity as measured by DASI. These findings highlight the need for anesthesiologists to include functional assessments in the preoperative evaluation of patients with a history of severe COVID-19. Integrating DASI into routine pre-anesthetic workup may improve risk stratification and perioperative outcomes in this vulnerable population.

Indexed as

anesthesiaCOVID-19Duke Activity Status Indexfunctional capacitypost-COVID syndromepreoperative evaluationVO2 max

Identifiers

PMID41551502
PMCPMC12808341

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.