Evidence map›Paper›PMID 41551433›Full record

Reviewnpj biomedical innovations2026

Don't judge an implant by its cover: how the foreign body response and fibrotic capsule might be harnessed for good.

Mary E Dickenson, Robert S Oakes, Aaron H Morris

Abstract readReview
In one paragraph

Review in npj biomedical innovations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Freeze-Dried CS/PVP/PVA Composite Scaffolds Doped with Curcumin and SiOInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Antigen-conjugated scaffolds enable sustained delivery of antigen and enrichment of antigen-specific T-cells.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mary E DickensonDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI USA.
Robert S OakesDepartment of Biomedical Engineering, University of Delaware, Newark, DE USA.
Aaron H MorrisDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI USA.

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
Supplement to Immunological Niches and Noninvasive Biosensors for Autoimmune MonitoringR00EB028840 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORRIS, AARON HARVEY · 2022 to 2025
$912k
BLRD VA IK2 BX005061National Science Foundation DGE2241144NIBIB NIH HHS R00 EB028840NIDCR NIH HHS T32 DE007057
6 · The paper itself

Abstract

Biomaterials are widely used, yet when implanted, they elicit a complex reaction from the host called the foreign body response (FBR). Although the FBR is typically viewed as a deleterious response to implants, many potential benefits of the FBR have recently been identified. This review highlights the variety of ways that the FBR has been harnessed for positive outcomes, including tissue engineering and disease monitoring.

Indexed as

BiomaterialsRegenerative medicineTissue engineering

Identifiers

PMID41551433
PMCPMC12811145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.