Evidence map›Paper›PMID 41551366›Full record

ArticleIDCases2026

A case of

Akinari Atsumi, Takahiro Asami, Takuya Ozawa, Takanori Asakura, Ho Namkoong, Takashi Inoue

Abstract read
In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akinari AtsumiDivision of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Takahiro AsamiDepartment of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan.
Takuya OzawaDivision of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Takanori AsakuraDivision of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Ho NamkoongDepartment of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
Takashi InoueDepartment of Internal Medicine, Sano Kosei General Hospital, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypersensitivity pneumonitis (HP) due to nontuberculous mycobacteria (NTM) is an uncommon phenotype of NTM pulmonary disease, classically linked to hot tub or pool exposure. We report a steroid-dependent case of HP-type Case presentation: A 79-year-old man with a 16-pack-year smoking history presented with progressive dyspnea on exertion. High-resolution CT showed bilateral peripheral ground-glass opacities, and serum Krebs von den Lungen-6 was markedly elevated. Bronchoalveolar lavage fluid demonstrated lymphocytic predominance with an increased CD4/CD8 ratio, fulfilling criteria for probable HP. Prednisolone induced clinical and radiological improvement; however, repeated attempts at tapering resulted in relapse with new ground-glass opacities in the right middle lobe and rising biomarkers. Although Conclusion: Antigen avoidance combined with azithromycin and ethambutol led to sustained clinical and radiological improvement and successful steroid tapering without restrictive ventilatory impairment. This case underscores the importance of routinely sending mycobacterial cultures from bronchoalveolar lavage in suspected HP and of carefully reassessing environmental exposures, even in outdoor settings, as identifying NTM as the causative antigen can substantially modify management.

Indexed as

Hot tub lungHypersensitivity pneumonitisMycobacterium aviumNTM-PD

Identifiers

PMID41551366
PMCPMC12811522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.