Evidence map›Paper›PMID 41551356›Full record

ArticleIDCases2026

Symmetrical lower extremity gangrene in a patient with severe malaria: a case report and literature review.

Sudi Temam Aman, Endrias Habte Belay, Tolasa Dibisa Jirata, Sherefudin Hassen Hussen, Siham Faris Isa, Abduletif Haji-Ababor Abagojam, Merid Lemma Kebede, Kidus Tesfaye Bezabih, Kedir Negesso Tukeni

Abstract readCase Reports
In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sudi Temam AmanDepartment of Orthopedics and Trauma, Jimma University, Jimma, Ethiopia.
Endrias Habte BelayDepartment of Orthopedics and Trauma, Jimma University, Jimma, Ethiopia.
Tolasa Dibisa JirataDepartment of Orthopedics and Trauma, Jimma University, Jimma, Ethiopia.
Sherefudin Hassen HussenDepartment of Orthopedics and Trauma, Jimma University, Jimma, Ethiopia.
Siham Faris IsaDepartment of Internal Medicine, Jimma University, Jimma, Ethiopia.
Abduletif Haji-Ababor AbagojamDepartment of General Surgery, Jimma University, Jimma, Ethiopia.
Merid Lemma KebedeDepartment of Radiology, Jimma University, Jimma, Ethiopia.
Kidus Tesfaye BezabihDepartment of Internal Medicine, Jimma University, Jimma, Ethiopia.
Kedir Negesso TukeniDepartment of Internal Medicine, Jimma University, Jimma, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Symmetrical peripheral gangrene (SPG) is an uncommon clinical entity characterized by bilateral ischemic damage resulting in gangrene, typically occurring in the absence of large-vessel occlusion or vasculitis. This case report describes a 14-year-old Ethiopian girl who developed SPG of the lower limbs in the context of severe Plasmodium falciparum malaria. She initially presented with fever, vomiting, and diarrhea, and despite prompt initiation of antimalarial therapy, progressive darkening of both feet was observed. Clinical evaluation revealed stable vital signs, preserved organ function, and palpable peripheral pulses, supporting the diagnosis of severe malaria complicated by peripheral gangrene. Management was conservative, relying on continued antimalarial treatment. This case highlights the importance of early recognition and timely intervention in SPG, underscoring the need to address underlying etiologies to optimize patient outcomes.

Indexed as

AnemiaEthiopiaGangreneJimma Medical CenterMalariaVasculitis

Identifiers

PMID41551356
PMCPMC12811545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.