Evidence map›Paper›PMID 41551329›Full record

SynthesisBioMed research international2026

Acceptance of HPV Vaccination: A Systematic Review of Knowledge, Attitudes and Barriers Among Healthcare Practitioners in Low- and Middle-Income Countries.

Nancy Innocentia Ebu Enyan, Mengying Zhang, Sebastian Ken-Amoah, Michelle King-Okoye, Joyce Agyeiwaa, Richard Sarfo-Walters, Dorothy Addo-Mensah, Patrick Kafui Akakpo, Dorcas Obiri-Yeboah, Lawrence Doi

Abstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nancy Innocentia Ebu EnyanDepartment of Public Health Nursing, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.ORCID https://orcid.org/0000-0002-3279-5800
Mengying ZhangNursing Studies, School of Health in Social Science, The University of Edinburgh, Edinburgh, UK, ed.ac.uk.
Sebastian Ken-AmoahDepartment of Obstetrics and Gynaecology, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.ORCID https://orcid.org/0000-0001-8293-6862
Michelle King-OkoyeRosemary Bryant Research Centre, University of South Australia, Adelaide, Australia, unisa.edu.au.
Joyce AgyeiwaaDepartment of Maternal and Child Health, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.
Richard Sarfo-WaltersDepartment of Adult Health, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.
Dorothy Addo-MensahDepartment of Adult Health, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.
Patrick Kafui AkakpoDepartment of Anatomic Pathology, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.
Dorcas Obiri-YeboahDepartment of Microbiology and Immunology, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.ORCID https://orcid.org/0000-0003-4562-9294
Lawrence DoiNursing Studies, School of Health in Social Science, The University of Edinburgh, Edinburgh, UK, ed.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer is one of the diseases that reflects global inequities. Vaccination against the human papillomavirus (HPV) is one of the main pillars of the World Health Organization (WHO) 2030 cervical cancer 90:70:90 elimination strategy. The role of healthcare practitioners in HPV vaccination acceptance cannot be overemphasized. This review investigated healthcare practitioners' knowledge, attitudes and barriers to promoting HPV vaccination in low- and middle-income countries (LMICs). Methods: A comprehensive search for relevant literature from 2006 to 2024 was conducted in the following databases: Web of Science, Scopus, MEDLINE, EMBASE, PsycINFO (via Ovid), Cochrane Library and CINAHL PLUS (via EBSCOhost). The included studies were published in the English language. Screening of eligible studies, data extraction and quality assessment were conducted in duplicate. The data was synthesise using narrative synthesis. Results: A total of 671 papers were identified from the database search, with seven studies meeting the criteria for inclusion. This review demonstrates varied levels of awareness, knowledge and attitudes of 136 healthcare practitioners in LMICs towards HPV vaccination. Although some studies demonstrated a positive attitude, others reported resistance towards the vaccine. The perceived barriers to HPV vaccination by healthcare practitioners identified were interpersonal, community-level and systemic in nature. Additionally, acceptance of HPV vaccination varied across the studies. Conclusions: This review highlights the need for capacity building programmes for healthcare practitioners in the area of HPV vaccination to enhance their knowledge and attitudes and develop contextually relevant interventions to eliminate the many barriers they encounter.

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticePapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareUterine Cervical NeoplasmsVaccinationDeveloping CountriesFemaleHealth PersonnelHumansPapillomavirus Vaccinesattitudeshealthcare practitionersHPV vaccination acceptancelow- and middle-income countries

Identifiers

PMID41551329
PMCPMC12809713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.