Evidence map›Paper›PMID 41551299›Full record

ArticleMDM policy & practice

Cost-Effectiveness of Risk-Based Screening for Asymptomatic Carotid Artery Stenosis.

Jinyi Zhu, Janice Jhang, Hanxuan Yu, Alvin I Mushlin, Hooman Kamel, Nathaniel Alemayehu, John C Giardina, Ajay Gupta, Ankur Pandya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MDM policy & practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jinyi ZhuDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID https://orcid.org/0000-0001-8169-5956
Janice JhangDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Hanxuan YuDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, TN, USA.
Alvin I MushlinDepartments of Population Health Sciences and of Medicine, Weill Cornell Medical College, New York, NY, USA.
Hooman KamelClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY, USA.
Nathaniel AlemayehuCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
John C GiardinaMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6618-1671
Ajay GuptaDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Ankur PandyaDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6130-2286

Funding

Development, Validation, and Application of a Stroke Policy Simulation ModelR01NS104143 · NINDS · HARVARD SCHOOL OF PUBLIC HEALTH · PI PANDYA, ANKUR · 2018 to 2022
$2.3M
NINDS NIH HHS R01 NS104143
6 · The paper itself

Abstract

Highlights: Targeted screening for asymptomatic carotid artery stenosis may be cost-effective only for adults aged 50 to 80 y at high atherosclerotic cardiovascular disease (ASCVD) risk.Screening individuals with a 10-y ASCVD risk greater than 30% could substantially reduce lifetime stroke burden while remaining within accepted US cost-effectiveness thresholds.Screening lower-risk (0%-20% 10-y ASCVD risk) adults provides minimal health gains at significantly higher costs and should not be recommended.Findings offer a decision-analytic framework to inform future screening guidelines and policy decisions as results from ongoing trials, such as CREST-2, become available.

Indexed as

asymptomatic carotid artery stenosiscost-effectiveness analysisscreeningstroke prevention

Identifiers

PMID41551299
PMCPMC12811569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.