Evidence map›Paper›PMID 41551221›Full record

ArticleJAC-antimicrobial resistance2026

Molecular mechanisms of disinfectant resistance in

Daniel J Noel, Alistair Bailey, Benjamin I Nicholas, Paul Skipp, C William Keevil, Sandra A Wilks

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel J NoelSchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0001-8560-4441
Alistair BaileySchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0003-0023-8679
Benjamin I NicholasSchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0003-1467-9643
Paul SkippSchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0002-2995-2959
C William KeevilSchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0003-1917-7706
Sandra A WilksSchool of Biological Sciences, University of Southampton, Highfield Campus, Southampton, UK.ORCID https://orcid.org/0000-0002-4134-9415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Chemical disinfectants are critical for infection control in healthcare environments and beyond, as exemplified by their vital role during the COVID-19 pandemic. Despite research repeatedly demonstrating that bacteria can develop adaptations that mitigate the efficacy of chemical disinfectants, the underlying molecular mechanisms remain poorly characterized. This study investigates the mechanisms that underpin resistance demonstrated by disinfectant-adapted Methods: Resistant samples have previously undergone long-term Results: Conclusions: These findings provide novel insights into how causative pathogens of healthcare-associated infections can adapt to and mitigate the effectiveness of common chemical disinfectants that are relied on globally every day as a critical infection control measure.

Identifiers

PMID41551221
PMCPMC12809559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.