Evidence map›Paper›PMID 41551184›Full record

ArticleCurrent research in food science2026

Parental sodium benzoate diet induces fat accumulation in offspring via histone H3K9me3 and SKN-1/Nrf2.

Zhongyu Fan, Han Zhang, Fang Liu, Yi Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chelerythrine enhances anti-fungi immunity inFrontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhongyu FanThe Key Laboratory of Pharmaceutical Research for Tumor Prevention and Treatment of the Education Department of Guizhou Province, Zunyi, Guizhou, 563000, China.
Han ZhangThe Key Laboratory of Pharmaceutical Research for Tumor Prevention and Treatment of the Education Department of Guizhou Province, Zunyi, Guizhou, 563000, China.
Fang LiuCollege of Basic Medicine, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Yi XiaoThe Key Laboratory of Pharmaceutical Research for Tumor Prevention and Treatment of the Education Department of Guizhou Province, Zunyi, Guizhou, 563000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium benzoate is a commonly used food preservative and chemical additive with well-established antimicrobial and antifungal activities, and is widely applied in the food, cosmetic, and pharmaceutical industries. Despite its extensive use, increasing evidence has raised concerns regarding its potential adverse effects on metabolic homeostasis, including the induction of oxidative stress, hepatic inflammation, lipid accumulation, and reduced lifespan. However, whether sodium benzoate-induced obesity phenotypes can be transmitted to subsequent generations via epigenetic mechanisms remains largely unexplored. In this study, we used

Indexed as

Fat accumulationHistone H3K9me3 complexSKN-1/Nrf2 signaling pathwaySodium benzoateTransgenerational epigenetic inheritance

Identifiers

PMID41551184
PMCPMC12808894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.