ReviewFrontiers in oncology2025
Electrophysiology of gliomas: current science, implications, and opportunities.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Radiation-activated astrocytes promote tumor progression through CXCL12 secretion and induce resistance to anti-PD-1 immunotherapy.Translational cancer research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gliomas engage in bidirectional communication with neurons, promoting hyperexcitable conditions that enable neural circuit infiltration and drive tumor growth. These neuron-glioma interactions create patterns of aberrant neural activity that can be detected using intracranial electrodes. While conventional clinical electrodes are limited by low spatiotemporal resolution and lack of single-unit precision, recent advances in neural engineering have introduced multiple types of high-density electrodes that provide orders of magnitude greater spatial resolution. Pairing these tools with emerging characterizations of novel, glioma-associated electrophysiological signatures offers new opportunities to understand disease progression and improve surgical and medical management for gliomas and glioma-related epilepsy. In this review, we begin by outlining foundational research in cancer neuroscience and neuron-glioma interactions through the lens of extracellular dynamics. We then discuss established and emerging methods for intraoperative evaluation of neural activity, what is known about glioma-associated oscillatory and aperiodic trends, and implications for future studies. Finally, we consider the therapeutic potential of neuromodulation for gliomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.