Evidence map›Paper›PMID 41551092›Full record

ArticleRadiology case reports2026

Iatrogenic hemoperitoneum and sigmoid colon injury from malpositioned apomorphine infusion device in advanced Parkinson's disease.

Connor Hughes, Timothy Fazio, Callum Umstad

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frailty in Parkinson's disease: time to integrate it into treatment decision-making?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Connor HughesDepartment of General Medicine, Royal Melbourne Hospital, Victoria, Australia.
Timothy FazioDepartment of General Medicine and Department of Metabolic's, Royal Melbourne Hospital, Victoria, Australia.
Callum UmstadDepartment of Radiology, Royal Melbourne Hospital, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apomorphine pumps are increasingly used for the management of patients with advanced Parkinson's Disease. We report a unique case of hemoperitoneum and penetrating colonic injury resulting from malpositioning of a subcutaneous apomorphine device-a complication not previously described in the literature. Seventy-six-year-old man with advanced Parkinson's Disease presented with acute abdominal pain 3-hours post the re-siting of his apomorphine infusion device. Contrast-enhanced computed tomography (CT) of the abdomen and pelvis revealed high-density fluid (47-67 Hounsfield Units), consistent with hemoperitoneum. Subsequent CT angiography revealed progressive bleeding and identified the infusion device penetrating the anterior sigmoid colon. The infusion set used was inappropriately long for the patient's anatomy, a major factor contributing to the complication. Patient-specific factors further increased the risk of bowel injury, including severe faecal loading with resultant stercoral colitis, minimal rectus abdominus musculature, and thin subcutaneous and preperitoneal fat, all of which was evident on CT imaging. The patient was managed conservatively based on consideration of comorbidities and frailty status, and made a full recovery. This case revealed a unique and rare iatrogenic injury resulting from a subcutaneous medication delivery device. Careful consideration of anatomical and patient-specific factors, along with appropriate device selection, is critical to preventing such complications.

Indexed as

Bowel perforationFaecal loadingHemoperitoneumIatrogenic injuryParkinson's diseaseSubcutaneous device

Identifiers

PMID41551092
PMCPMC12811225

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.