Evidence map›Paper›PMID 41550976›Full record

ReviewIBRO neuroscience reports2026

Progress on experimental models of neuromyelitis optica spectrum disease.

Guo Yawen, Yao Shunyu, Jiang Daiyi, Lin Lanxin, Wu Siliang, Peng Yong

Abstract readReview
In one paragraph

Review in IBRO neuroscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guo YawenDepartment of Neurology, Provincial Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine, Zhuzhou 412000, China.
Yao ShunyuDepartment of Neurology, Provincial Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine, Zhuzhou 412000, China.
Jiang DaiyiDepartment of Neurology, Provincial Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine, Zhuzhou 412000, China.
Lin LanxinDepartment of Neurology, Provincial Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine, Zhuzhou 412000, China.
Wu SiliangDepartment of Neurology and Geriatrics, The First Affiliated Hospital of Hunan Traditional Chinese Medical College (Hunan Provincial Directly Affiliated Hospital of Traditional Chinese Medicine), Zhuzhou 412000, China.
Peng YongDepartment of Neurology, Provincial Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine, Zhuzhou 412000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica spectrum disease (NMOSD) is an inflammatory demyelinating disease of the central nervous system (CNS) that primarily affects the optic nerve and spinal cord. At present, the etiology and pathogenesis of NMOSD have not been fully clarified, and its treatment is not perfect, and ideal animal models are a key tool to explore the disease mechanism and screen therapeutic drugs. In recent years, the discovery and confirmation of neuromyelitis optica immunoglobulin G (anti-AQP4 antibodies) as aquaporin-4 (AQP4)-specific antibodies have greatly promoted the study of the pathogenesis of NMOSD, and the study of animal models of NMOSD has become a hot topic of current attention. This article reviews the research progress of NMOSD animal models in recent years, providing a reference for further promoting the in-depth understanding of NMOSD and the formulation of treatment plans.

Indexed as

Animal modelsAQP4Neuromyelitis optica

Identifiers

PMID41550976
PMCPMC12805297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.