Evidence map›Paper›PMID 41550837›Full record

ArticleSage open pediatrics

Clinical Characteristics and Resistance Patterns of Extensively Drug-Resistant

Hamna Khalid, Zoha Rehman, Malik Muhammad Kabir, Noshaba Razaq, Kanza Riaz, Zavata Afnan, Muhammad Dawood Nazir, Noof K Binashikhbubkr

Abstract read
In one paragraph

Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hamna KhalidWah Medical College, Wah Cantt, Pakistan.ORCID https://orcid.org/0009-0005-5414-1356
Zoha RehmanWah Medical College, Wah Cantt, Pakistan.ORCID https://orcid.org/0009-0001-3317-5662
Malik Muhammad KabirWah Medical College, Wah Cantt, Pakistan.
Noshaba RazaqWah Medical College, Wah Cantt, Pakistan.
Kanza RiazWah Medical College, Wah Cantt, Pakistan.
Zavata AfnanWah Medical College, Wah Cantt, Pakistan.
Muhammad Dawood NazirWah Medical College, Wah Cantt, Pakistan.
Noof K BinashikhbubkrHadhramout University, Mukalla, Yemen.ORCID https://orcid.org/0000-0001-7391-4709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To describe the demographics, clinical characteristics, antimicrobial resistance profiles, and treatment responses of pediatric XDR Introduction: XDR Methods: A prospective cohort study was conducted at POF Hospital, Northern Punjab (January 2024-January 2025), enrolling 65 children (1-12 years) with culture-confirmed XDR Results: Most patients (60%) were aged 5 to 10 years; vomiting (69.2%) and headache (47.7%) were frequent. All isolates were resistant to ceftriaxone, ciprofloxacin, and first-line agents; meropenem and azithromycin remained 100% and 96.9% susceptible. Severe disease was associated with delayed fever clearance ( Conclusion: XDR typhoid demands strengthened stewardship, vaccination, and water safety.

Indexed as

antibiotic resistanceazithromycinCRPmeropenempediatric typhoidsalmonella typhiXDR typhoid

Identifiers

PMID41550837
PMCPMC12811554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.