ArticleRSC advances2026
A high-copper-content metal-organic framework with potential antibacterial activities.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 authors.
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Abstract
Despite recent significant advancements in antibacterial applications of copper-based metal-organic frameworks (Cu MOFs), the synthesis of a high-copper-content MOF remains elusive. Here we proposed a multi-coordination strategy through a direct solvothermal reaction of Cu ions and formic acid, which yielded a three-dimensional MOF (denoted as Cu-FA) containing 32% Cu. Through single crystal X-ray diffraction analyses, the precise spatial structure of Cu-FA was determined. Two types of Cu⋯O coordination bonds with varying bond energies were found in Cu-FA, enabling a multistage Cu release protocol to balance the antibacterial efficacy and biocompatibility. As a result, Cu-FA presented significant antibacterial activity against
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Registered trials
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