Evidence map›Paper›PMID 41550826›Full record

ArticleRSC advances2026

A selective fluorescent probe for an organophosphorous nerve agent mimic

Muhammad Shar Jhahan Khan, K S Al-Namshah, Muhammad Saleem, Ya-Wen Wang

Erratum issuedAbstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Muhammad Shar Jhahan KhanDepartment of Chemistry, Ghazi University Pakistan seemab35usa@gmail.com.ORCID https://orcid.org/0009-0007-0824-5482
K S Al-NamshahDepartment of Chemistry, Imam Mohammad bnI Saud Islamic University Saudi Arabia KSNamshah@imamu.edu.sa.
Muhammad SaleemDepartment of Chemistry, Ghazi University Pakistan msaleem@gudgk.edu.pk.
Ya-Wen WangSchool of Chemistry, Southwest Jiaotong University China ywwang@swjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A class of chemical warfare agents and their facile use in terrorist attacks underscores the need to develop accurate system to detect these chemicals. For this paper, we synthesized and developed a new highly selective and sensitive fluorescence probe based on fluoresceinyloxime for the detection of a nerve agent mimic. The synthesized probe underwent an abnormal cascade reaction from oxime to isoxazole in DMF/HEPES buffer (1/1, v/v, pH 7.0). The probe responded by quenching the fluorescence intensity in very short time (within seconds) and gave a naked eye detection by changing the colour of the solution from dark orange to very light green with a detection limit of 0.18 µM. The probe not only shows sensitivity and selectivity in the liquid phase, but can also be applied for the detection of nerve agents in the vapour phase with a clear colour change easily observed by the naked eye.

Identifiers

PMID41550826
PMCPMC12809880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.