Evidence map›Paper›PMID 41550624›Full record

ArticleJournal of cardiology cases2026

Total clinical course of left insular stroke-induced bradycardia-tachycardia and takotsubo syndrome: A case report of stroke-heart syndrome.

Keisuke Kawai, Yusuke Kihara, Hajime Iguchi, Masaharu Ishihara, Minoru Kishi, Masahide Iwai, Hiroya Sakuramoto

Abstract readCase Reports
In one paragraph

Article in Journal of cardiology cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Keisuke KawaiDepartment of Cardiovascular Medicine, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.
Yusuke KiharaDepartment of Internal Medicine, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.
Hajime IguchiDepartment of Neurosurgery, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.
Masaharu IshiharaDepartment of Cardiovascular and Renal Medicine, Hyogo Medical University, Hyogo, Japan.
Minoru KishiDepartment of Internal Medicine, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.
Masahide IwaiDepartment of Internal Medicine, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.
Hiroya SakuramotoDepartment of Cardiovascular Medicine, Nishiwaki City Hospital, Nishiwaki, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the total course of left insular stroke-induced bradycardia-tachycardia and takotsubo syndrome in a 71-year-old woman. The patient presented with aphasia and right hemiparesis, and was diagnosed with acute stroke involving the left insular cortex. Eight hours after admission, she exhibited bradycardia-tachycardia syndrome with atrial fibrillation. On day 2 of hospitalization, T-wave inversions of the electrocardiogram were first observed, and echocardiography revealed reduced contraction exclusively at the left ventricular apex, which disappeared on day 35. The T-wave inversion deepened twice afterward. On days 10 and 12 of hospitalization, she experienced asystole episodes of 10.9 and 10.6 s, respectively, without losing consciousness. After day 22, her heart rate never dropped below 40 beats/min during admission. The patient's heart rate remained above 50 beats/min for 21 months after hospital discharge. Learning objective: A left insular stroke can induce bradycardia-tachycardia syndrome, and the time to resolution of the conduction disturbance was 22 days after the initial stroke event. Given the delayed recovery of the cardiac conduction system in stroke-induced bradycardia, there may be unnecessary device implantations. In hemodynamically stable patients with bradycardia due to insular stroke, it may be advisable to wait longer before implanting a permanent pacemaker.

Indexed as

Bradycardia-tachycardiaInsular strokeStroke-heart syndromeTakotsubo

Identifiers

PMID41550624
PMCPMC12805423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.